Early Symptoms in Symptomatic and Preclinical Genetic Frontotemporal Lobar Degeneration

OBJECTIVES: The clinical heterogeneity of Frontotemporal Dementia (FTD) complicates identification of biomarkers for clinical trials that may be sensitive during the pre-diagnostic stage. It is not known whether cognitive or behavioural changes during the preclinical period are predictive of genetic...

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Published in:J Neurol Neurosurg Psychiatry
Main Authors: Tavares, Tamara P., Mitchell, Derek G.V., Coleman, Kristy K. L., Coleman, Brenda L., Shoesmith, Christen, Butler, Chris, Santana, Isabel, Danek, Adrian, Gerhard, Alexander, de Mendonça, Alexandre, Borroni, Barbara, Tartaglia, Carmela, Graff, Caroline, Galimberti, Daniela, Tagliavini, Fabrizio, Moreno, Fermin, Frisoni, Giovanni, Rowe, James, Levin, Johannes, van Swieten, John, Otto, Markus, Synofzik, Matthis, Sanchez-Valle, Raquel, Vandenberghe, Rik, Laforce, Robert, Ghidoni, Roberta, Sorbi, Sandro, Ducharme, Simon, Masellis, Mario, Rohrer, Jonathan D., Finger, Elizabeth C.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611534/
https://ncbi.nlm.nih.gov/pubmed/32769115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2020-322987
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