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Tolcapone in Obsessive Compulsive disorder: A Randomized Double-Blind Placebo-Controlled Crossover Trial

OBJECTIVE: Despite the availability of evidence-based treatments for obsessive-compulsive disorder (OCD), not all patients experience sufficient benefit or are able to tolerate them. Tolcapone is a catechol-o-methyl-transferase (COMT) enzyme inhibitor that augments cortical dopaminergic transmission...

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Detalhes bibliográficos
Publicado no:Int Clin Psychopharmacol
Main Authors: Grant, Jon E., Hook, Roxanne, Valle, Stephanie, Chesivoir, Eve, Chamberlain, Samuel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611531/
https://ncbi.nlm.nih.gov/pubmed/34310432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YIC.0000000000000368
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