Nicotinamide for the treatment of heart failure with preserved ejection fraction*

Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent and intractable form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we show that diastolic dysfunction in patients with HFpEF is associated with a cardiac deficit in nicotinamide adenine din...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Abdellatif, Mahmoud, Trummer-Herbst, Viktoria, Koser, Franziska, Durand, Sylvère, Adão, Rui, Vasques-Nóvoa, Francisco, Freundt, Johanna K., Voglhuber, Julia, Pricolo, Maria-Rosaria, Kasa, Michael, Türk, Clara, Aprahamian, Fanny, Herrero-Galán, Elías, Hofer, Sebastian J., Pendl, Tobias, Rech, Lavinia, Kargl, Julia, Anto-Michel, Nathaly, Ljubojevic-Holzer, Senka, Schipke, Julia, Brandenberger, Christina, Auer, Martina, Schreiber, Renate, Koyani, Chintan N., Heinemann, Akos, Zirlik, Andreas, Schmidt, Albrecht, von Lewinski, Dirk, Scherr, Daniel, Rainer, Peter P., von Maltzahn, Julia, Mühlfeld, Christian, Krüger, Marcus, Frank, Saša, Madeo, Frank, Eisenberg, Tobias, Prokesch, Andreas, Leite-Moreira, Adelino F., Lourenço, André P., Alegre-Cebollada, Jorge, Kiechl, Stefan, Linke, Wolfgang A., Kroemer, Guido, Sedej, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611499/
https://ncbi.nlm.nih.gov/pubmed/33568522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abd7064
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