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Mutational landscape of receptor guanylyl cyclase C: Functional analysis and disease-related mutations
Guanylyl cyclase C (GC-C) is the receptor for the heat-stable enterotoxin, which causes diarrhea, and the endogenous ligands, guanylin and uroguanylin. GC-C is predominantly expressed in the intestinal epithelium and regulates fluid and ion secretion in the gut. The receptor has a complex domain org...
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| Publicado no: | IUBMB Life |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611479/ https://ncbi.nlm.nih.gov/pubmed/32293781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2283 |
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