Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia

INTRODUCTION: The presymptomatic phase of neurodegenerative disease can last many years, with sustained cognitive function despite progressive atrophy. We investigate this phenomenon in familial Frontotemporal dementia (FTD). METHODS: We studied 121 presymptomatic FTD mutation carriers and 134 famil...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Tsvetanov, Kamen A., Gazzina, Stefano, Simon Jones, P., van Swieten, John, Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, LaforceJr, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Otto, Markus, Frisoni, Giovanni, Ghidoni, Roberta, Sorbi, Sandro, Rohrer, Jonathan D., Rowe, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611220/
https://ncbi.nlm.nih.gov/pubmed/33215845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12209
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