Functional genetic variants of the IFN-λ3 (IL28B) gene and transcription factor interactions on its promoter

Interferon lambda 3 (IFN-λ3 or IFNL3, formerly IL28B), a type III interferon, modulates immune responses during infection/inflammation. Several human studies have reported an association of single nucleotide polymorphisms (SNP) in the IFNL3 locus with expression level of IFNL3. Previous genetic stud...

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Publicado en:Cytokine
Autores principales: Roy, Subhajit, Roy, Debarati Guha, Bhushan, Anand, Bharatiya, Seema, Chinnaswamy, Sreedhar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611124/
https://ncbi.nlm.nih.gov/pubmed/33725487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2021.155491
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