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N-Methyl-D-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats

Experimental and clinical studies suggest that the low-affinity N-methyl-D-aspartate (NMDA) receptor open-channel blockers Mg(2+) and memantine are effective in reducing trigeminal nociceptive activation. The aim of the present study was to investigate the apparent effectiveness of these channel blo...

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Pubblicato in:Eur J Neurosci
Autori principali: Hoffmann, Jan, Storer, Robin James, Park, Jeong-Wook, Goadsby, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611086/
https://ncbi.nlm.nih.gov/pubmed/31009120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14423
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