Drugs that inhibit TMEM16 proteins block SARS-CoV-2 Spike-induced syncytia

COVID-19 is a disease with unique characteristics including lung thrombosis (1), frequent diarrhoea (2), abnormal activation of the inflammatory response(3) and rapid deterioration of lung function consistent with alveolar oedema(4). The pathological substrate for these findings remains elusive. Her...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Braga, Luca, Ali, Hashim, Secco, llaria, Chiavacci, Elena, Neves, Guilherme, Goldhill, Daniel, Penn, Rebecca, Jimenez-Guardeño, Jose M., Ortega-Prieto, Ana M., Bussani, Rossana, Cannatà, Antonio, Rizzari, Giorgia, Collesi, Chiara, Schneider, Edoardo, Arosio, Daniele, Shah, Ajay M., Barclay, Wendy S., Malim, Michael H., Burrone, Juan, Giacca, Mauro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611055/
https://ncbi.nlm.nih.gov/pubmed/33827113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03491-6
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