Crystal Structure of the E1 Component of the Escherichia coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex

The thiamine-dependent E1o component (EC 1.2.4.2) of the 2-oxoglutarate dehydrogenase complex catalyses a rate-limiting step of the tricarboxylic acid cycle (TCA) of aerobically respiring organisms. We describe the crystal structure of Escherichia coli E1o in its apo and holo forms at 2.6 Å and 3.5...

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Udgivet i:J Mol Biol
Main Authors: Frank, René A. W., Price, Amanda J., Northrop, Fred D., Perham, Richard N., Luisi, Ben F.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611002/
https://ncbi.nlm.nih.gov/pubmed/17367808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.080
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