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Readfish enables targeted nanopore sequencing of gigabase-sized genomes

Nanopore sequencers can be used to selectively sequence certain DNA molecules in a pool by reversing the voltage across individual nanopores to reject specific sequences, enabling enrichment and depletion to address biological questions. Previously, we achieved this using dynamic time warping to map...

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Dettagli Bibliografici
Pubblicato in:Nat Biotechnol
Autori principali: Payne, Alexander, Holmes, Nadine, Clarke, Thomas, Munro, Rory, Debebe, Bisrat J, Loose, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610616/
https://ncbi.nlm.nih.gov/pubmed/33257864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-00746-x
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