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A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome
The mechanistic target of rapamycin complex 1 (mTORC1) is a key metabolic hub that controls the cellular response to environmental cues by exerting its kinase activity on multiple substrates(1–3). However, whether mTORC1 responds to diverse stimuli by differentially phosphorylating specific substrat...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610377/ https://ncbi.nlm.nih.gov/pubmed/32612235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2444-0 |
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