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Impaired nicotinamide adenine dinucleotide (NAD(+)) metabolism in diabetes and diabetic tissues: Implications for nicotinamide‐related compound treatment

One of the biochemical abnormalities found in diabetic tissues is a decrease in the cytosolic oxidized to reduced forms of the nicotinamide adenine dinucleotide ratio (NAD(+)/NADH also known as pseudohypoxia) caused by oxidation of excessive substrates (glucose through the polyol pathway, free fatty...

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Bibliographische Detailangaben
Veröffentlicht in:J Diabetes Investig
Hauptverfasser: Fan, Lan, Cacicedo, Jose M., Ido, Yasuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610120/
https://ncbi.nlm.nih.gov/pubmed/32428995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13303
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