Quaternary Ammonium Compound Disinfectants Reduce Lupus-Associated Splenomegaly by Targeting Neutrophil Migration and T-Cell Fate

Hypersensitivity reactions and immune dysregulation have been reported with the use of quaternary ammonium compound disinfectants (QACs). We hypothesized that QAC exposure would exacerbate autoimmunity associated with systemic lupus erythematosus (lupus). Surprisingly, however, we found that compare...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Abdelhamid, Leila, Cabana-Puig, Xavier, Mu, Qinghui, Moarefian, Maryam, Swartwout, Brianna, Eden, Kristin, Das, Prerna, Seguin, Ryan P., Xu, Libin, Lowen, Sarah, Lavani, Mital, Hrubec, Terry C., Jones, Caroline N., Luo, Xin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609861/
https://ncbi.nlm.nih.gov/pubmed/33193366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.575179
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