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Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT‐20 and TtT/GF by affecting expression of MMP‐14 and ADAM12

Selective estrogen receptor modulators (SERMs) significantly affect survival and invasiveness of rodent pituitary adenoma (PA) cells. The impact of three clinically relevant SERMs (bazedoxifene, clomiphene, raloxifene) on invasiveness and on gene and protein expression of invasion‐related proteases...

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Publicat a:FEBS Open Bio
Autors principals: Zhang, Zhuo, Bartsch, Jörg W., Benzel, Julia, Lei, Ting, Nimsky, Christopher, Voellger, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609764/
https://ncbi.nlm.nih.gov/pubmed/33030286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12999
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