Complement C1q Interacts With LRP1 Clusters II and IV Through a Site Close but Different From the Binding Site of Its C1r and C1s-Associated Proteases

LRP1 is a large endocytic modular receptor that plays a crucial role in the scavenging of apoptotic material through binding to pattern-recognition molecules. It is a membrane anchored receptor of the LDL receptor family with 4 extracellular clusters of ligand binding modules called cysteine rich co...

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Vydáno v:Front Immunol
Hlavní autoři: Fouët, Guillaume, Gout, Evelyne, Wicker-Planquart, Catherine, Bally, Isabelle, De Nardis, Camilla, Dedieu, Stéphane, Chouquet, Anne, Gaboriaud, Christine, Thielens, Nicole M., Kleman, Jean-Philippe, Rossi, Véronique
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609443/
https://ncbi.nlm.nih.gov/pubmed/33193398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583754
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