Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53

Our preliminary study shows that cinnamaldehyde (CA) could protect against intestinal ischemia/reperfusion (I/R) injuries, in which p53 and NF-κB p65 play a synergistic role. In this study, we conducted in vivo and in vitro experiments to verify this proposal. SD rats were pretreated with CA (10 or...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Almoiliqy, Marwan, Wen, Jin, Xu, Bin, Sun, Yu-chao, Lian, Meng-qiao, Li, Yan-li, Qaed, Eskandar, Al-Azab, Mahmoud, Chen, Da-peng, Shopit, Abdullah, Wang, Li, Sun, Peng-yuan, Lin, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609352/
https://ncbi.nlm.nih.gov/pubmed/32238887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0359-9
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