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Endosomal Organization of CpG-constructs Correlates with Enhanced Immune Activation

This paper describes how the endosomal organization of immuno-stimulatory nanoconstructs can tune the in vitro activation of macrophages. Nanoconstructs composed of gold nanoparticles conjugated with unmethylated cytosine-phosphate-guanine (CpG) oligonucleotides have distinct endosomal distributions...

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Bibliografische gegevens
Gepubliceerd in:Nano Lett
Hoofdauteurs: Lee, Kwahun, Huang, Ziyin N., Mirkin, Chad A., Odom, Teri W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609249/
https://ncbi.nlm.nih.gov/pubmed/32787186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c02536
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