A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids

Three-dimensional (3D) culture systems have fueled hopes to bring about the next generation of more physiologically relevant high-throughput screens (HTS). However, current protocols yield either complex but highly heterogeneous aggregates (‘organoids’) or 3D structures with less physiological relev...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Renner, Henrik, Grabos, Martha, Becker, Katharina J, Kagermeier, Theresa E, Wu, Jie, Otto, Mandy, Peischard, Stefan, Zeuschner, Dagmar, TsyTsyura, Yaroslav, Disse, Paul, Klingauf, Jürgen, Leidel, Sebastian A, Seebohm, Guiscard, Schöler, Hans R, Bruder, Jan M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Stem Cells and Regenerative Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609049/
https://ncbi.nlm.nih.gov/pubmed/33138918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52904
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