Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury

BACKGROUND: The glomerulus is a specialized capillary bed that is involved in urine production and BP control. Glomerular injury is a major cause of CKD, which is epidemic and without therapeutic options. Single-cell transcriptomics has radically improved our ability to characterize complex organs,...

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Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Chung, Jun-Jae, Goldstein, Leonard, Chen, Ying-Jiun J., Lee, Jiyeon, Webster, Joshua D., Roose-Girma, Merone, Paudyal, Sharad C., Modrusan, Zora, Dey, Anwesha, Shaw, Andrey S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2020
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609001/
https://ncbi.nlm.nih.gov/pubmed/32651223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020020220
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