Chest computed tomography outcomes in a randomized clinical trial in cystic fibrosis: Lessons learned from the first ataluren phase 3 study

A phase 3 randomized double blind controlled, trial in 238 people with cystic fibrosis (CF) and at least one nonsense mutation (nmCF) investigated the effect of ataluren on FEV(1). The study was of 48 weeks duration and failed to meet its primary endpoint. Unexpectedly, while FEV(1) declined, chest...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tiddens, Harm A. W. M., Andrinopoulou, Eleni-Rosalina, McIntosh, Joe, Elborn, J. Stuart, Kerem, Eitan, Bouma, Nynke, Bosch, Jochem, Kemner-van de Corput, Mariette
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608929/
https://ncbi.nlm.nih.gov/pubmed/33141825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240898
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares