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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males

Large portions of eukaryotic genomes consist of transposable elements (TEs), and the establishment of transcription-repressing heterochromatin during early development safeguards genome integrity in Drosophila. Repeat-rich Y chromosomes can act as reservoirs for TEs (‘toxic’ Y effect), and incomplet...

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Foilsithe in:Nat Commun
Main Authors: Wei, Kevin H.-C., Gibilisco, Lauren, Bachtrog, Doris
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608633/
https://ncbi.nlm.nih.gov/pubmed/33139741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19134-9
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