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Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates

The heterotrimeric NatC complex, comprising the catalytic Naa30 and the two auxiliary subunits Naa35 and Naa38, co-translationally acetylates the N-termini of numerous eukaryotic target proteins. Despite its unique subunit composition, its essential role for many aspects of cellular function and its...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Grunwald, Stephan, Hopf, Linus V. M., Bock-Bierbaum, Tobias, Lally, Ciara C. M., Spahn, Christian M. T., Daumke, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608589/
https://ncbi.nlm.nih.gov/pubmed/33139728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19321-8
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