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Human Spermatogenesis Tolerates Massive Size Reduction of the Pseudoautosomal Region

Mammalian male meiosis requires homologous recombination between the X and Y chromosomes. In humans, such recombination occurs exclusively in the short arm pseudoautosomal region (PAR1) of 2.699 Mb in size. Although it is known that complete deletion of PAR1 causes spermatogenic arrest, no studies h...

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Détails bibliographiques
Publié dans:Genome Biol Evol
Auteurs principaux: Fukami, Maki, Fujisawa, Yasuko, Ono, Hiroyuki, Jinno, Tomoko, Ogata, Tsutomu
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608489/
https://ncbi.nlm.nih.gov/pubmed/32785664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evaa168
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