Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions

Brain tumors are dynamic complex ecosystems with multiple cell types. To model the brain tumor microenvironment in a reproducible and scalable system, we developed a rapid three-dimensional (3D) bioprinting method to construct clinically relevant biomimetic tissue models. In recurrent glioblastoma,...

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Published in:Cell Res
Main Authors: Tang, Min, Xie, Qi, Gimple, Ryan C., Zhong, Zheng, Tam, Trevor, Tian, Jing, Kidwell, Reilly L., Wu, Qiulian, Prager, Briana C., Qiu, Zhixin, Yu, Aaron, Zhu, Zhe, Mesci, Pinar, Jing, Hui, Schimelman, Jacob, Wang, Pengrui, Lee, Derrick, Lorenzini, Michael H., Dixit, Deobrat, Zhao, Linjie, Bhargava, Shruti, Miller, Tyler E., Wan, Xueyi, Tang, Jing, Sun, Bingjie, Cravatt, Benjamin F., Muotri, Alysson R., Chen, Shaochen, Rich, Jeremy N.
Format: Artigo
Language:Inglês
Published: Springer Singapore 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608409/
https://ncbi.nlm.nih.gov/pubmed/32499560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0338-1
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