Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is a poor-prognosis cancer type with limited understanding of its molecular etiology. Using 508 ESCC genomes, we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’ outcomes....

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Cell Res
Główni autorzy: Cui, Yongping, Chen, Hongyan, Xi, Ruibin, Cui, Heyang, Zhao, Yahui, Xu, Enwei, Yan, Ting, Lu, Xiaomei, Huang, Furong, Kong, Pengzhou, Li, Yang, Zhu, Xiaolin, Wang, Jiawei, Zhu, Wenjie, Wang, Jie, Ma, Yanchun, Zhou, Yong, Guo, Shiping, Zhang, Ling, Liu, Yiqian, Wang, Bin, Xi, Yanfeng, Sun, Ruifang, Yu, Xiao, Zhai, Yuanfang, Wang, Fang, Yang, Jian, Yang, Bin, Cheng, Caixia, Liu, Jing, Song, Bin, Li, Hongyi, Wang, Yi, Zhang, Yingchun, Cheng, Xiaolong, Zhan, Qimin, Li, Yanhong, Liu, Zhihua
Format: Artigo
Język:Inglês
Wydane: Springer Singapore 2020
Hasła przedmiotowe:
Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608103/
https://ncbi.nlm.nih.gov/pubmed/32398863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0333-6
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