Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas

Both somatic hypermutation (SHM) and class switch recombination (CSR) are initiated by activation-induced cytidine deaminase (AID). Dysregulation of these processes has been linked to B cell lymphomagenesis. Here we performed an in-depth analysis of diffuse large B cell lymphoma (DLBCL) and follicul...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Ye, Xiaofei, Ren, Weicheng, Liu, Dongbing, Li, Xiaobo, Li, Wei, Wang, Xianhuo, Meng, Fei-Long, Yeap, Leng-Siew, Hou, Yong, Zhu, Shida, Casellas, Rafael, Zhang, Huilai, Wu, Kui, Pan-Hammarström, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Technical Advances and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608067/
https://ncbi.nlm.nih.gov/pubmed/33136155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200573
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