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The anti-scarring effect of corneal stromal stem cell therapy is mediated by transforming growth factor β3

BACKGROUND: Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent stromal tissue in injured corneas. These effects rely on factors produced by CSSC to block the fibrotic gene expression. This study investigated the mechanism of the scar-...

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Bibliografiske detaljer
Udgivet i:Eye Vis (Lond)
Main Authors: Weng, Lin, Funderburgh, James L., Khandaker, Irona, Geary, Moira L., Yang, Tianbing, Basu, Rohan, Funderburgh, Martha L., Du, Yiqin, Yam, Gary Hin-Fai
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607765/
https://ncbi.nlm.nih.gov/pubmed/33292650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40662-020-00217-z
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