PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive Microenvironment

BACKGROUND AND AIMS: Pyruvate kinase M2 (PKM2) is an essential regulator of the Warburg effect, but its biological function promoting immune escape of hepatocellular carcinoma (HCC) is unclear. METHODS: GEPIA web tool and immunohistochemistry (IHC) analysis were employed to evaluate the clinical rel...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Li, Tian-En, Wang, Shun, Shen, Xiao-Tian, Zhang, Ze, Chen, Mo, Wang, Hao, Zhu, Ying, Xu, Da, Hu, Bei-Yuan, Wei, Ran, Zheng, Yan, Dong, Qiong-Zhu, Qin, Lun-Xiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606949/
https://ncbi.nlm.nih.gov/pubmed/33193421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.589997
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