Lack Of APOE Christchurch Variant In Five Age Of Onset Outliers With PSEN1, PSEN2 Alzheimer Disease And MAPT Frontotemporal Dementia

INTRODUCTION: Age of onset modifiers are of considerable importance in Alzheimer and related dementias. Arboleta-Valesquez et al, reporting on a single PSEN1 subject, suggested that homozygosity for the Christchurch variant of APOE could represent such a modifier. METHODS: We studied APOE Christchur...

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Bibliographic Details
Published in:J Neurol Sci
Main Authors: Yu, Chang-En, Chen, Sunny, Jayadev, Suman, Bird, Thomas
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606829/
https://ncbi.nlm.nih.gov/pubmed/32977230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2020.117143
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