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Impact of baseline serum IL-8 on metastatic hormone-sensitive prostate cancer outcomes in the Phase 3 CHAARTED trial (E3805)
BACKGROUND: The immunosuppressive cytokine IL-8, produced by tumor cells and some myeloid cells, promotes inflammation, angiogenesis, and metastasis. In our discovery work, elevated serum IL-8 at androgen deprivation therapy (ADT) initiation portended worse overall survival (OS). Leveraging serum sa...
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| Publicado no: | Prostate |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606809/ https://ncbi.nlm.nih.gov/pubmed/32949185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.24074 |
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