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O-Pair Search with MetaMorpheus for O-glycopeptide Characterization

We report O-Pair Search, a new approach to identify O-glycopeptides and localize O-glycosites. Using paired collision- and electron-based dissociation spectra, O-Pair Search identifies O-glycopeptides using an ion-indexed open modification search and localizes O-glycosites using graph theory and pro...

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Publicat a:Nat Methods
Autors principals: Lu, Lei, Riley, Nicholas M., Shortreed, Michael R., Bertozzi, Carolyn R., Smith, Lloyd M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606753/
https://ncbi.nlm.nih.gov/pubmed/33106676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-00985-5
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