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Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling

Climbing fibers (CFs) from the inferior olive (IO) make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites, and trigger distinctive responses known as complex spikes (CSs). We find that in awake mice, a CS in one PC suppresses conventional simple spikes (SSs) in neighboring PCs...

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Podrobná bibliografie
Vydáno v:Nat Neurosci
Hlavní autoři: Han, Kyung-Seok, Chen, Christopher H., Khan, Mehak M., Guo, Chong, Regehr, Wade G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606706/
https://ncbi.nlm.nih.gov/pubmed/32895566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0701-z
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