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Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling

Climbing fibers (CFs) from the inferior olive (IO) make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites, and trigger distinctive responses known as complex spikes (CSs). We find that in awake mice, a CS in one PC suppresses conventional simple spikes (SSs) in neighboring PCs...

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Bibliografski detalji
Izdano u:Nat Neurosci
Glavni autori: Han, Kyung-Seok, Chen, Christopher H., Khan, Mehak M., Guo, Chong, Regehr, Wade G.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606706/
https://ncbi.nlm.nih.gov/pubmed/32895566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0701-z
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