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Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling
Climbing fibers (CFs) from the inferior olive (IO) make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites, and trigger distinctive responses known as complex spikes (CSs). We find that in awake mice, a CS in one PC suppresses conventional simple spikes (SSs) in neighboring PCs...
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| Publicado en: | Nat Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606706/ https://ncbi.nlm.nih.gov/pubmed/32895566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0701-z |
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