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Csx3 is a cyclic oligonucleotide phosphodiesterase associated with type III CRISPR–Cas that degrades the second messenger cA(4)

Cas10 is the signature gene for type III CRISPR–Cas surveillance complexes. Unlike type I and type II systems, type III systems do not require a protospacer adjacent motif and target nascent RNA associated with transcriptionally active DNA. Further, target RNA recognition activates the cyclase domai...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Brown, Sharidan, Gauvin, Colin C., Charbonneau, Alexander A., Burman, Nathaniel, Lawrence, C. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606696/
https://ncbi.nlm.nih.gov/pubmed/32826317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014099
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