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Molecular mechanisms of FasL-mediated ‘reverse-signaling’
Effector lymphocytes, including NK and T cells, express FasL. Expression of Fas, the receptor for FasL in tumor cells, renders them susceptible to NK and T cell-mediated killing. The functional relevance of FasL in initiating death signals in tumor cells is well-characterized. However, the cytoplasm...
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| Publicado no: | Mol Immunol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606657/ https://ncbi.nlm.nih.gov/pubmed/32905906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2020.08.010 |
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