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Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone

Advanced glycation end-products (AGEs) deteriorate bone strength. Among over 40 species identified in vivo, AGEs other than pentosidine were roughly estimated as total fluorescent AGEs (tfAGEs) due to technical difficulties. Using LC-QqTOF-MS, we established a system that enabled the quantitation of...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Arakawa, Shoutaro, Suzuki, Ryusuke, Kurosaka, Daisaburo, Ikeda, Ryo, Hayashi, Hiroteru, Kayama, Tomohiro, Ohno, Rei-ichi, Nagai, Ryoji, Marumo, Keishi, Saito, Mitsuru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606603/
https://ncbi.nlm.nih.gov/pubmed/33139851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75923-8
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