Nimodipine improves cortical efficiency during working memory in healthy subjects

The L-type calcium channel gene, CACNA1C, is a validated risk gene for schizophrenia and the target of calcium channel blockers. Carriers of the risk-associated genotype (rs1006737 A allele) have increased frontal cortical activity during working memory and higher CACNA1C mRNA expression in the pref...

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Udgivet i:Transl Psychiatry
Main Authors: Zink, Caroline F., Giegerich, Mellissa, Prettyman, Greer E., Carta, Kayla E., van Ginkel, Marcus, O’Rourke, Molly P., Singh, Eesha, Fuchs, Edward J., Hendrix, Craig W., Zimmerman, Eric, Breakey, Jennifer, Marzinke, Mark A., Hummert, Pamela, Pillai, Jay J., Weinberger, Daniel R., Bigos, Kristin L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606375/
https://ncbi.nlm.nih.gov/pubmed/33139710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01066-z
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