Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial

BACKGROUND: Persistent hyperlactatemia has been considered as a signal of tissue hypoperfusion in septic shock patients, but multiple non-hypoperfusion-related pathogenic mechanisms could be involved. Therefore, pursuing lactate normalization may lead to the risk of fluid overload. Peripheral perfus...

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Vydáno v:Ann Intensive Care
Hlavní autoři: Castro, Ricardo, Kattan, Eduardo, Ferri, Giorgio, Pairumani, Ronald, Valenzuela, Emilio Daniel, Alegría, Leyla, Oviedo, Vanessa, Pavez, Nicolás, Soto, Dagoberto, Vera, Magdalena, Santis, César, Astudillo, Brusela, Cid, María Alicia, Bravo, Sebastian, Ospina-Tascón, Gustavo, Bakker, Jan, Hernández, Glenn
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606372/
https://ncbi.nlm.nih.gov/pubmed/33140173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00767-4
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