An Improved Sequencing-Based Bioinformatics Pipeline to Track the Distribution and Clonal Architecture of Proviral Integration Sites

The combined application of linear amplification-mediated PCR (LAM-PCR) protocols with next-generation sequencing (NGS) has had a large impact on our understanding of retroviral pathogenesis. Previously, considerable effort has been expended to optimize NGS methods to explore the genome-wide distrib...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Rosewick, Nicolas, Hahaut, Vincent, Durkin, Keith, Artesi, Maria, Karpe, Snehal, Wayet, Jérôme, Griebel, Philip, Arsic, Natasa, Marçais, Ambroise, Hermine, Olivier, Burny, Arsène, Georges, Michel, Van den Broeke, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606357/
https://ncbi.nlm.nih.gov/pubmed/33193242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.587306
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