Effect of functional BDNF and COMT polymorphisms on symptoms and regional brain volume in Frontotemporal Dementia and Corticobasal Syndrome

OBJECTIVE: To assess the effects of the common functional polymorphisms Brain-Derived Neurotrophic Factor (BDNF) val66met and Catechol O-methyltransferase (COMT) val158met on the cognitive, neuropsychiatric, motor symptoms, and MRI findings in participants with Frontotemporal Lobar Degeneration (FTL...

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Bibliografiske detaljer
Udgivet i:J Neuropsychiatry Clin Neurosci
Main Authors: Huey, Edward D., Fremont, Rachel, Manoochehri, Masood, Gazes, Yunglin, Lee, Seonjoo, Cosentino, Stephanie, Tierney, Michael, Wassermann, Eric M., Momeni, Parastoo, Grafman, Jordan
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606216/
https://ncbi.nlm.nih.gov/pubmed/32397876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.neuropsych.19100211
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