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Therapeutic Activity of Type 3 Streptococcus pneumoniae Capsule Degrading Enzyme Pn3Pase

PURPOSE: Streptococcus pneumoniae (Spn) serotype 3 (Spn3) is considered one of the most virulent serotypes with resistance to conventional vaccine and treatment regimens. Pn3Pase is a glycoside hydrolase that we have previously shown to be highly effective in degrading the capsular polysaccharide of...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Paschall, Amy V., Middleton, Dustin R., Wantuch, Paeton L., Avci, Fikri Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605875/
https://ncbi.nlm.nih.gov/pubmed/33140159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02960-3
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