Chargement en cours...
Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development
The 2,2,7-trimethylguanosine (TMG) cap is one of the first identified modifications on eukaryotic RNAs. TMG, synthesized by the conserved Tgs1 enzyme, is abundantly present on snRNAs essential for pre-mRNA splicing. Results from ex vivo experiments in vertebrate cells suggested that TMG ensures nucl...
Enregistré dans:
| Publié dans: | PLoS Genet |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605716/ https://ncbi.nlm.nih.gov/pubmed/33085660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009098 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|