Targeting Yes1 Associated Transcriptional Regulator Inhibits Hepatocellular Carcinoma Progression and Improves Sensitivity to Sorafenib: An in vitro and in vivo Study

PURPOSE: The aim of this study was to investigate the role of Yes1 associated transcriptional regulator (YAP1) in the pathology of hepatocellular carcinoma (HCC) and its potential as a therapeutic target. METHODS: YAP1 expression in HCC and adjacent tissues was determined via immunohistochemistry; i...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Guo, Liwen, Zheng, Jiaping, Luo, Jun, Zhang, Zhewei, Shao, Guoliang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove 2020
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605682/
https://ncbi.nlm.nih.gov/pubmed/33149619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S249412
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