Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression, and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays an integral role in regulating vascular barrier function physio...

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Publicat a:bioRxiv
Autors principals: Wang, Li, Astone, Matteo, Alam, Sk. Kayum, Zhu, Zhu, Pei, Wuhong, Frank, David A., Burgess, Shawn M., Hoeppner, Luke H.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605565/
https://ncbi.nlm.nih.gov/pubmed/33140053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.27.358374
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