SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway

SARS-CoV-2 can infect multiple organs, including lung, intestine, kidney, heart, liver, and brain. The molecular details of how the virus navigates through diverse cellular environments and establishes replication are poorly defined. Here, we performed global proteomic analysis of the virus-host int...

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Publicado en:bioRxiv
Autores principales: Chen, Da-Yuan, Khan, Nazimuddin, Close, Brianna J., Goel, Raghuveera K., Blum, Benjamin, Tavares, Alexander H., Kenney, Devin, Conway, Hasahn L., Ewoldt, Jourdan K., Kapell, Sebastian, Chitalia, Vipul C., Crossland, Nicholas A., Chen, Christopher S., Kotton, Darrell N., Baker, Susan C., Connor, John H., Douam, Florian, Emili, Andrew, Saeed, Mohsan
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605551/
https://ncbi.nlm.nih.gov/pubmed/33140044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.27.358259
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