High levels of SARS-CoV-2–specific T cells with restricted functionality in severe courses of COVID-19

BACKGROUND: Patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in the severity of disease. We hypothesized that characteristics of SARS-CoV-2–specific immunity correlate with disease severity. METHODS: In this study, SARS-CoV-2–specific T cells and antibodies...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Schub, David, Klemis, Verena, Schneitler, Sophie, Mihm, Janine, Lepper, Philipp M., Wilkens, Heinrike, Bals, Robert, Eichler, Hermann, Gärtner, Barbara C., Becker, Sören L., Sester, Urban, Sester, Martina, Schmidt, Tina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605520/
https://ncbi.nlm.nih.gov/pubmed/32937615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142167
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