Binding mechanism and structural insights into the identified protein target of COVID-19 and importin-α with in-vitro effective drug ivermectin

While an FDA approved drug Ivermectin was reported to dramatically reduce the cell line of SARS-CoV-2 by ∼5000 folds within 48 h, the precise mechanism of action and the COVID-19 molecular target involved in interaction with this in-vitro effective drug are unknown yet. Among 12 different COVID-19 t...

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Podrobná bibliografie
Vydáno v:J Biomol Struct Dyn
Hlavní autoři: Sen Gupta, Parth Sarthi, Biswal, Satyaranjan, Panda, Saroj Kumar, Ray, Abhik Kumar, Rana, Malay Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605516/
https://ncbi.nlm.nih.gov/pubmed/33111618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1839564
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