Metabolic labeling of RNA using multiple ribonucleoside analogs enables the simultaneous evaluation of RNA synthesis and degradation rates

Gene expression is determined by a balance between RNA synthesis and RNA degradation. To elucidate the underlying regulatory mechanisms and principles of this, simultaneous measurements of RNA synthesis and degradation are required. Here, we report the development of “Dyrec-seq,” which uses 4-thiour...

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Detaylı Bibliyografya
Yayımlandı:Genome Res
Asıl Yazarlar: Kawata, Kentaro, Wakida, Hiroyasu, Yamada, Toshimichi, Taniue, Kenzui, Han, Han, Seki, Masahide, Suzuki, Yutaka, Akimitsu, Nobuyoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2020
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605267/
https://ncbi.nlm.nih.gov/pubmed/32843354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.264408.120
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