Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes

The recent identification of recurrently mutated epigenetic regulator genes (ERGs) supports their critical role in tumorigenesis. We conducted a pan-cancer analysis integrating (epi)genome, transcriptome, and DNA methylome alterations in a curated list of 426 ERGs across 33 cancer types, comprising...

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Pubblicato in:Genome Res
Autori principali: Halaburkova, Andrea, Cahais, Vincent, Novoloaca, Alexei, Araujo, Mariana Gomes da Silva, Khoueiry, Rita, Ghantous, Akram, Herceg, Zdenko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605261/
https://ncbi.nlm.nih.gov/pubmed/32963031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.268292.120
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