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Serial Measurement of Cell-Cycle Arrest Biomarkers [TIMP-2] · [IGFBP7] and Risk for Progression to Death, Dialysis, or Severe Acute Kidney Injury in Patients with Septic Shock

Rationale: Urinary TIMP-2 (tissue inhibitor of metalloproteinases-2) and IGFBP7 (insulin-like growth factor–binding protein 7) can predict acute kidney injury (AKI) in patients with sepsis. Objectives: To address critical questions about whether biomarkers can inform the response to treatment and wh...

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Bibliographic Details
Published in:Am J Respir Crit Care Med
Main Authors: Fiorentino, Marco, Xu, Zhongying, Smith, Ali, Singbartl, Kai, Palevsky, Paul M., Chawla, Lakhmir S., Huang, David T., Yealy, Donald M., Angus, Derek C.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605192/
https://ncbi.nlm.nih.gov/pubmed/32584598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201906-1197OC
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