Knockout of the Circadian Clock Protein PER1 Results in Sex-Dependent Alterations of ET-1 Production in Mice in Response to a High Salt Diet plus Mineralocorticoid Treatment

Previously, we showed that global knockout (KO) of the circadian clock transcription factor PER1 in male, but not female, mice fed a high salt diet plus mineralocorticoid treatment (HS/DOCP) resulted in non-dipping hypertension and decreased night/day ratio of sodium (Na) excretion. Additionally, we...

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Publicado no:Can J Physiol Pharmacol
Main Authors: Douma, Lauren G., Crislip, G. Ryan, Cheng, Kit-Yan, Barral, Dominique, Masten, Sarah, Holzworth, Meaghan, Roig, Emilio, Glasford, Krystal, Beguiristain, Kevin, Li, Wendy, Bratanatawira, Phillip, Lynch, I. Jeanette, Cain, Brian D., Wingo, Charles S., Gumz, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605171/
https://ncbi.nlm.nih.gov/pubmed/32437627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2019-0688
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